Professor Hugh Markus

Professor Hugh Markus graduated from Cambridge and Oxford Universities. He trained in General Medicine at Oxford and Nottingham, and then Neurology at the Middlesex and University College Hospitals London, and then at St George's and Atkinson Morley Neuroscience Centre, London.

He was appointed Senior Lecturer, and subsequently Reader in Neurology at King's College School of Medicine and Dentistry in 1994, and then to the Foundation Chair in Neurology at St George's Hospital Medical School in January 2000. He is an Honorary Consultant at St George's Hospital and Atkinson Morley Neuroscience Centre.

His clinical interest is in stroke. He is lead clinician for stroke services at St George's Healthcare. He covers the acute stroke unit, which is within Neurology in the Atkinson Morley Neuroscience Centre, as well as carrying out specialised clinics for transient ischaemic attack, Carotid Artery Disease including assessment for Carotid Stenting, Subcortical Stroke, and CADASIL.

His research interests are in using imaging and molecular genetic approaches to investigate the pathogenesis of stroke and there are internationally renowned teams working in both of these areas at St George's. The department has imaging expertise in a number of techniques including Duplex Ultrasound and Transcranial Doppler Ultrasound (particularly Emboli detection), MRI (including perfusion, diffusion tensor and spectroscopy), Xenon CT perfusion measurements, and contrast perfusion CT. He also supervises a stroke genetics laboratory.

He has been involved in a number of clinical trials in different aspects of stroke care. These include Chairman of the steering committee for CARESS (Clopidogrel and Aspirin for Reduction of Emboli in Symptomatic Carotid Stenosis), and CHIPPS (Blood Pressure Lowering and Elevation in Acute Stroke) and is principal investigator for ACES (Asymptomatic Carotid Emboli Study) and the UK Genetics Group Lacuna/DNA Bank.

He is Chairman of the Scientific Committee of the British Association of Stroke Physicians and is editor-in-chief of Stroke Review as well as being on the editorial board of other neurology and stroke journals. He has published over 150 publications in peer-reviewed journals and two books on stroke.



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