Professor David Oliveira - Professor of Renal Medicine (MD., F.R.C.P.)

Professor David Oliveira studied medicine at Cambridge University as well as Westminster Hospital Medical School where he qualified in 1979. Following five years in a variety of hospital medical jobs (with an emphasis on renal medicine) he completed a PhD in cellular immunology as an MRC Training Fellow at University College London.

In 1995, Professor Oliveira was appointed Foundation Professor of Renal Medicine/Honorary Consultant Nephrologist at St. George's University of London. In 2001 he was appointed Dean for Research & Development, also at St George's University of London, and Director of Research & Development for St George's Healthcare NHS Trust. Since June 2007 he has relinquished his Research & Development posts in order to become Course Director for the new combined MBBS course at St George's University of London. Professor Oliveira has also held a position as a Non-executive Director of Epsom and St Helier University Hospitals NHS Trust since December 2005.

His clinical research interests include trials of immunosuppressants (phase I and II work with Sirolimus in Cambridge, phase III work at St George's) and other aspects of treatment in renal medicine. Experimental research focuses on drug-induced autoimmunity, and the role and mechanisms of mast cell and Th2 cell activation in this process.

Some of Professor Oliveira's most important peer-reviewed publications include:

Oliveira DBG, Blackwell N, Virchis AE, Axelrod RA. T helper and T suppressor cells are restricted by the A and E molecules, respectively, in the F antigen system. Immunogenetics 1985; 22: 169-75.

Oliveira DBG, Nardi NB. Immune suppression genes control the anti-F antigen response in F1 hybrids and recombinant inbred sets of mice. Immunogenetics 1987; 26: 359-365.

Mathieson PW, Cobbold SP, Hale G, Clark MJ, Oliveira DBG, Lockwood CM, Waldmann H. Monoclonal antibody therapy in systemic vasculitis. N Engl J Med 1990; 323: 250-254.

Schofield JP, Vijayakumar RK, Oliveira DBG. Sequences of the mouse F protein alleles and identification of a T cell epitope. Eur J Immunol 1991; 21: 1235-1240.

Esnault VLM, Mathieson PW, Thiru S, Oliveira DBG, Lockwood CM. Autoantibodies to myeloperoxidase in Brown Norway rats treated with mercuric chloride. Lab Invest 1992; 67: 114-120.

Mathieson PW, Thiru S, Oliveira DBG. Mercuric chloride-treated Brown Norway rats develop widespread tissue injury including necrotizing vasculitis. Lab Invest 1992; 67: 121-129.

Mathieson PW, Thiru S, Oliveira DBG. Regulatory role of OX22+ T cells in mercury-induced autoimmunity in the Brown Norway rat. J Exp Med 1993; 177: 1309-1316.

Mathieson PW, Wurzner R, Oliveira DBG, Lachmann PJ, Peters DK.Complement-mediated adipocyte lysis by nephritic factor sera. J Exp Med 1993; 177: 1827-1831.

Zhang L, Jayne DRW, Zhao MH, Lockwood CM, Oliveira DBG. The distribution of MHC class II alleles in primary systemic vasculitis. Kidney Int 1995; 47: 294-298.

Oliveira DBG, Gillespie K, Wolfreys K, Mathieson PW, Qasim F, Coleman JW. Compounds that induce autoimmunity in the Brown Norway rat sensitize mast cells for mediator release and IL-4 expression. Eur J Immunol 1995; 25: 2259-2264.

Kiely PDW, Gillespie KM, Oliveira DBG. Oxpentifylline inhibits tumour necrosis factor?mRNA transcription and protects against arthritis in the mercuric chloride-treated Brown Norway rat. Eur J Immunol 1995; 25: 2899-2906.

Wolfreys K, Oliveira DBG. Alterations in intracellular reactive oxygen species generation and redox potential modulate mast cell function. Eur J Immunol 1997; 27: 297-306.

Kiely PDW, Pecht I, Oliveira DBG. Mercuric chloride-induced vasculitis in the Brown Norway rat: ab T-cell dependent and -independent phases: role of the mast cell. J Immunol 1997; 159: 5100-5106.

Oliveira DBG. Membranous nephropathy: an IgG4 mediated disease. Lancet 1998; 351: 670-671.

Wu Z, Turner DR, Oliveira DBG. Interleukin (IL)-4 gene expression upregulated by mercury in rat mast cells: a role of oxidant stress in IL-4 transcription. Int Immunol 2001; 13: 297-304.

Wu Z, MacPhee IAM, Oliveira DBG. Reactive oxygen species in the initiation of IL-4 driven autoimmunity as a potential therapeutic target. Curr Pharm Des 2004; 10: 899-913.

Vinen CS, Turner DR, Oliveira DBG. A role for ?? T cells in the resistant phase of the Brown Norway rat model of vasculitis. Clin Exp Immunol 2005; 140: 32-40.

Go back to experts

More on our Specialist Services

Latest news

Charitable Contributions in 2019

02nd Jan 2020

As the 2019 year comes to an end, we would like to recognize the substantial charitable contributions made by the

Read more ›

Richmond Pharmacology to provide Immediate Life Support (ILS) Courses

31st Jul 2019

In line with our on-going commitment to providing quality training and promoting the highest safety standard,

Read more ›

Echocardiography Course undertaken at Richmond Pharmacology

13th Mar 2019

Richmond Pharmacology CEO, Dr Jorg Taubel, Franklin Gordon, Resuscitation Simulation & Clinical Skills Practitioner

Read more ›

Pharmacology 2019 by British Pharmacological Society

British Pharmacological Society’s flagship annual meeting. Dr. Richard Francis-Sakai will be presenting our latest

View event ›