Cardiac Safety
![Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668da469ac54233244fefcf3_Screenshot%202024-07-09%20225806.png)
Confirmation of the cardiac safety of nolasiban in a randomised cohort of healthy female volunteers
July 9, 2024
View publication![Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e2df36454b2a311202882_Screenshot%202024-07-10%20084500.png)
Novel antisense therapy targeting microRNA-132 in patients with heart failure: results of a first-in-human Phase 1b randomized, double-blind, placebo-controlled study
July 9, 2024
View publication![Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668da00780afd77787945078_Screenshot%202024-07-09%20223928.png)
Haemodynamic effects of the nitroxyl donor cimlanod (BMS-986231) in chronic heart failure: a randomized trial
July 9, 2024
View publication![Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668d8dc75b0ea1f1d4db7ca8_Screenshot%202024-07-09%20212108.png)
Comparing the consistency of electrocardiogram interval measurements by resting ECG versus 12-lead Holter
July 9, 2024
View publication![CRISPR-Cas9 in-vivo gene editing shows reduction in TTR after a single dose](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/60dada54db0b97102f38d385_image%2086.jpg)
CRISPR-Cas9 in-vivo gene editing shows reduction in TTR after a single dose
June 29, 2021
View publication![Meta-analysis of the effect of a meal on QTcF](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5fd0f63405b523c68b0430f5_JSCPT-thumb.jpg)
![Effects of progesterone and estradiol on QT subintervals over the course of a menstrual cycle](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5f69fea6acb840e32eab71cd_C18030_thumb.png)
Effects of progesterone and estradiol on QT subintervals over the course of a menstrual cycle
September 22, 2020
View publication![Do hERG blocking agents further increase the risk of sudden cardiac death in patients with type 1 diabetes?](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5f69fc9b7b91a71b3b72a32a_C12.061-thumb.png)
Do hERG blocking agents further increase the risk of sudden cardiac death in patients with type 1 diabetes?
September 22, 2020
View publication![Assay Sensitivity in QT Assessment](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec4d4603da379a028ccf6_Taubel-2015_published.jpg)
![Single Doses up to 800 mg of E-52862](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec37e5a4c5e7a76c9e060_journal-74x100.jpg)
![Concentration-Effect Modeling Based on Change From Baseline](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec2f5d1a7a30b63ec7b0b_Pages-from-Ferber-et-al-JCP-2014-2-pg-1-74x100.jpg)
![Analyzing the Relationship of QT Interval and Exposure to Nitazoxanide](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec2523098584ce501d829_Pages-from-Taubel-et-al-Nitazoxanide-TQT-study-jcph300_2014-pg-1-74x100.jpg)
Analyzing the Relationship of QT Interval and Exposure to Nitazoxanide
February 20, 2020
View publication![Comparison of the effects of levofloxacin on QT/QTc interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec1c16eb85d72c4b478d2_Sugiyama-et-al-74x100.jpg)
![Bupivacaine Extended Release Liposome Injection](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec0c95a4c5e22aac8c367_Naseem-et-al-2011-74x100.jpg)
![Levofloxacin can be used as a positive control in QT/QTc](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec0156d0f8e4fa6ca4a55_bcp_3595_rpl-74x100.jpg)
![Shortening of the QT Interval After Food](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebf88603da33b2c25b2d5_Taubel-et-al-2011-2-1-74x100.jpg)
![Comparison of Six Commonly Used QT Correction Models and Their Parameter Estimation Methods](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebeee8f9bf2780e0cc5a1_Comparison-of-QT-Correction-Methods-P1-2-69x100.jpg)
Comparison of Six Commonly Used QT Correction Models and Their Parameter Estimation Methods
February 20, 2020
View publication![Investigating the Ethnic Differences between the Effect of Moxifloxacin on Cardiac Conduction](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebe32feca87f6c042e8db_2014-Ethnic-Differences-QTc-J-Taubel-DIA-Japan-4-0-PUBLIC-2-74x74.jpg)
Investigating the Ethnic Differences between the Effect of Moxifloxacin on Cardiac Conduction
February 20, 2020
View publication![Mason-Likar electrode configuration](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebdb75a912b4419088500_YJELC_51352-74x100.jpg)
![Thorough QT study of the effect of oral moxifloxacin on QTc interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebd25e7c28f5b2f7a9bdd_bcp12168-p1-74x100.jpg)
Thorough QT study of the effect of oral moxifloxacin on QTc interval
February 20, 2020
View publication![Lamotrigine does not prolong QTc in TQT studies](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ebb2515bb0e18a9632c3e_Lamotrigine-74x100.jpg)
![Insulin at normal physiological levels does not prolong QTc interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea7f88f9bf212b600f21a_Taubel-et-al-Insulin-does-not-prolong-the-QTc-interval-BJCP-FINAL-74x100.jpg)
Insulin at normal physiological levels does not prolong QTc interval
February 20, 2020
View publication![Repeated supratherapeutic dosing of strontium ranelate](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea7a0d72d12772ecf4caf_Repeated-supratherapeutic-dosing-of-strontium-ranelate-over-15-days-does-not-prolong-QTc-interval-in-healthy-volunteers-74x100.jpg)
![The Power Of Phase I Studies To Detect Clinically Relevant Qtc Prolongation](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e75f7e55980ba88cb9385_jscpt-24-11-14-a3-74x100.jpg)
The Power Of Phase I Studies To Detect Clinically Relevant Qtc Prolongation
February 20, 2020
View publication![Investigating the effect of intravenous APD421 (Amilsulpride) and the ethnic differences](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea64ab123879545020d3b_jscpt-2015-74x70.jpg)
Investigating the effect of intravenous APD421 (Amilsulpride) and the ethnic differences
February 20, 2020
View publication![Confirmation of the Cardiac Safety of Rupatadine in a Single Ascending Dose and Multiple Ascending Dose](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea599feca87dd93375e29_Rupatadine-in-Japanese-v2-PRINT-74x70.jpg)
Confirmation of the Cardiac Safety of Rupatadine in a Single Ascending Dose and Multiple Ascending Dose
February 20, 2020
View publication![Late Changes After a Euglycaemic Insulin Clamp](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea4bcbc6a7033d4802c72_ACCP_2012_2-74x70.jpg)
![Comparison of digital 12-lead ECG and digital 12-lead holter ECG](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea43caa48f8582473df0c_ASCPT_Holter-vs-Digital_Final-Version_230211_-74x70.jpg)
![Retrospective Validation using PK-PD modelling of ECG data](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea3c25a4c5e60d9b966a6_Esteve_ACCP-Poster-tiny-version-74x70.jpg)
![The Impact of Insulin Levels on QTc Interval in Thorough QT Studies](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea33eecb2611408cc1250_ACCP_2012_1-74x70.jpg)
The Impact of Insulin Levels on QTc Interval in Thorough QT Studies
February 20, 2020
View publication![Moxifloxacin effect on QTc interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea20c116ec6acebe6ec49_DIA-Washington-2012-Evolving-Science-Track-2-16APR2012-74x74.jpg)
![Retrospective analysis of ECG data](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea170d1a7a30bcddb7fb7_Evgen-Pharma-Logo-70x100.jpg)
![Alternative methods for the confirmation of assay sensitivity in Thorough QT studies](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ea039aa48f81eb37229a1_JSCPT_Alternative-methods_Final-Version_23-74x70.jpg)
Alternative methods for the confirmation of assay sensitivity in Thorough QT studies
February 20, 2020
View publication![Sex differences on the effect of moxifloxacin](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9fe06eb85da887a3feef_JSCPT_Sex-Difference_Final-Version_23-11-11-74x70.jpg)
![QT prolongation in healthy Japanese subjects](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9f2e8f9bf27b95fbd6ea_JSCPT_Moxifloxacin-effect-and-race_Final-Version_23-11-11-74x70.jpg)
![The 24 Hour Profile of Moxifloxacin Effect on QTc](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9e156fb1970588392b9f_24hr-74x70.jpg)
![Confirmation of the Cardiac Safety of OBE022](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9e156fb1970588392b9f_24hr-74x70.jpg)
![Estimation of the Power of the Food Effect on QTc](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9d8b5ab2a86e234f06b7_Ferber-et-al-2017-thumb.jpg)
![Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9d10309858a6c8ed78c2_Taubel-2017-Cardiac-safety-of-rupatadine-thumb.jpg)
Cardiac Safety of Rupatadine in a Single-Ascending-Dose and Multiple-Ascending-Dose
February 20, 2020
View publication![Comparison of ECG Parameters Using GE Getemed Continuous ECG Holter and MAC-1200 Bedside ECG](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9c7355f0576c31aca339_bedside-ecg-web-thumb-71x100.jpg)
Comparison of ECG Parameters Using GE Getemed Continuous ECG Holter and MAC-1200 Bedside ECG
February 20, 2020
View publication![Assessment of C-Peptide Effects on Cardiac Ion Channel Currents](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e62eebe8904e99aa3265f_C-peptide-effects-Thumb.jpg)
![Confirmation of the Cardiac Safety of P218](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a9225b0790b28cdef1d_Malaria-prevention-thumb.pdf.jpg)
![A Phase I study to investigate the effects of Clascoterone on QT interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a17ecb2617671c7b2e3_clasct-71x100.jpg)
A Phase I study to investigate the effects of Clascoterone on QT interval
February 20, 2020
View publication![The cardiovascular effects of a meal](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e99406eb85d4ab7a1263f_peak-int-71x100.jpg)
![Diurnal Profile of the QTc Interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e96edf9ba251a2de829a8_encore-thumb-71x100.jpg)
![Confirmation of the Cardiac Safety of PGF2α Receptor Antagonist](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e80a32003493181271bbc_OBE022-thumb-71x100.jpg)
![Influence of calcium blockade on the QT effects of a meal](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e75f7e55980ba88cb9385_jscpt-24-11-14-a3-74x100.jpg)
![Concentration-QTC Analysis of a Cholinomimetic Agent](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e75f7e55980ba88cb9385_jscpt-24-11-14-a3-74x100.jpg)
![Do hERG blocking agents further increase](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e75f7e55980ba88cb9385_jscpt-24-11-14-a3-74x100.jpg)
![The differences between two algorithms](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e62eebe8904e99aa3265f_C-peptide-effects-Thumb.jpg)
![Sex differences in subinterval measurements](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e62eebe8904e99aa3265f_C-peptide-effects-Thumb.jpg)
![Sex Hormones and the QT Interval](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e62eebe8904e99aa3265f_C-peptide-effects-Thumb.jpg)
Clinical Pharmacology and Adaptive Early Phase Studies
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e28592934ba4d6a6434d1_Screenshot%202024-07-10%20082107.png)
A randomized, open‑label two‑period crossover pilot study to evaluate the relative bioavailability in the fed state of atovaquone‑proguanil (Atoguanil™) versus atovaquone‑proguanil hydrochloride (Malarone®) in healthy adult participants
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e2685d0d6e2e81d1e3aa7_Screenshot%202024-07-10%20081319.png)
The Value of In-Person Contact in Clinical Trials: A Qualitative Study examining Patient Attitudes towards Trial Visits conducted at a Contract Research Organisation
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e260be26de768466c5011_Screenshot%202024-07-10%20081117.png)
Association for Human Pharmacology in the Pharmaceutical Industry conference 2022: impending change, innovations and future challenges
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e25a37738f34100eeabf9_Screenshot%202024-07-10%20080930.png)
Blinding Is Seeing: A Single-Centre Study Into the Viability of Auto-Injectors for Blinded-Drug Administration in Randomised Controlled Trials
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e25100bd9e07612155ff3_Screenshot%202024-07-10%20080706.png)
Concentration-QT modelling of the novel DHFR inhibitor P218 in healthy male volunteers
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e2e3e1f8e1e0f8528e6b7_Screenshot%202024-07-10%20084615.png)
Unanticipated CNS Safety Signal in a Placebo-Controlled, Randomized Trial of Co-Administered Atovaquone-Proguanil and Amodiaquine
July 10, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668da132a3e112ece804188e_Screenshot%202024-07-09%20224428.png)
Ethnic Sensitivity Study of the Extrafine, Single-Inhaler, Triple Therapy Beclomethasone Dipropionate, Formoterol Fumarate, and Glycopyrronium Bromide Pressurized Metered Dose Inhaler in Japanese and Caucasian Healthy Individuals
July 9, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668da06d75b848b7a64b61cd_Screenshot%202024-07-09%20224112.png)
A Phase 1 Study to Investigate the Effects of Cortexolone 17α-Propionate, Also Known as Clascoterone, on the QT Interval Using the Meal Effect to Demonstrate ECG Assay Sensitivity
July 9, 2024
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4edabbf9ba25257a0b59b7_Pages-from-1471-2288-14-84-74x100.jpg)
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![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed859046e09d0c07a3034_1471-2466-14-52-74x100.jpg)
Transient paradoxical bronchospasm associated with inhalation of the LAMA AZD9164
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed7825a912b463e159941_The-practical-application-of-adaptive-study-design-in-early-phase-clinical-trials_A-retrospective-analysis-of-time-savings-74x100.jpg)
The practical application of adaptive study design in early phase clinical trials
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed6585f5ebee26038d9b1_Richmond-Pharmacology-Ltd-2-2-70x100.jpg)
Rule Britannia – the advantages of conducting first-time-in-human (FTIH) studies in the UK
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed5a33f13bd15898d7867_Cizolirtine-71x100.jpg)
Cizolirtine Citrate (E-4018) in the Treatment of Chronic Neuropathic Pain
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed458f9ba25041206e480_Xu-et-al-2011-74x100.jpg)
Pharmacokinetics, pharmacodynamics and safety of a human anti-IL-6 monoclonal antibody (sirukumab)
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed38f6fb19774c254bb8c_Effects-71x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed2b56fb197cf4f5437bf_ASCPT2013MuellerSingle_26FebFINAL-74x51.jpg)
Ascending single-dose study with ACT-280778, a non-dihydropyridine, dual L- and T-type calcium channel blocker
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ed16d5a912b737a12a335_ACCP2014-poster-2014-a3-74x70.jpg)
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The influence of a low fat diet and hospitalisation on liver function tests
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ece73ce21f9222b7a9bee_NRES_organon-research-summary-71x100.jpg)
A phase I, randomised single center, open-label parallel group trial to compare the pharmacokinetics
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ecd249e82e94c80e18967_TMC125-71x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ecc9f6a32cff7266b896d_Evgen-BPS-poster-tiny-web-70x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ecc431e700f13a2d437c0_ACCP_PET500_Final-Draft-Version_070910-74x69.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ecbadbac39a593fd50334_TMC207-74x71.jpg)
The pharmacokinetic interaction between isoniazid/pyrazinamide and TMC207
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ec7ce6eb85d8f58b7b4ab_Clincal-Trials-A-Practical-Guide-74x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a9225b0790b28cdef1d_Malaria-prevention-thumb.pdf.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a9225b0790b28cdef1d_Malaria-prevention-thumb.pdf.jpg)
The Pharmacokinetic Interaction of the Selective PGF2α Receptor Antagonist OBE022
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a9225b0790b28cdef1d_Malaria-prevention-thumb.pdf.jpg)
Pharmacokinetics and Safety of the Oral Prostaglandin F2 alpha Receptor Antagonist OBE022
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4e9a9225b0790b28cdef1d_Malaria-prevention-thumb.pdf.jpg)
Japanese Studies
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ee2ed8c74e87c806514bb_JAS-023-poster-PRINT-1-70x100.jpg)
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![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ee23baa48f85a0391c9aa_Rupatadine-Japanese-Volunteers-PRINT-FINAL-74x70.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ee1a61c72ab036bba806b_GASTRIC-ACID-SUPPRESION-EFFECT-OF-TAK-438-MRD-74x79.jpg)
Gastric Acid Suppression Effect of TAK-438, A Potassium-Competitive Acid Blocker
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4ee0505a912bc2b11af73c_fentanyl-72x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4edea0d1a7a33e6bfb35f3_GASTRIC-ACID-SUPPRESION-EFFECT-OF-TAK-438-SRD-74x79.jpg)
Gastric Acid Suppression Effect of TAK-438, A Potassium-Competitive Acid Blocker
February 20, 2020
View publication![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4edc8dbc6a700d629df79d_Similar-71x100.jpg)
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/5e4edbaa55f0575ea0cbca1b_ERS-JSAD-JMAD-poster_5-7-74x57.jpg)
The safety, tolerability and pharmacokinetics of AZD5069, a novel CXCR2 antagonist
February 20, 2020
View publicationPatient Studies
![](https://cdn.prod.website-files.com/5e4bf3ffdec34954e2ccd80b/668e255f7943f3ffb1f3c99c_Screenshot%202024-07-10%20080823.png)
A first-in-human phase 1 study of cavrotolimod, a TLR9 agonist spherical nucleic acid, in healthy participants: Evidence of immune activation
July 10, 2024
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