First transdermal patch to treat schizophrenia hits market

Posted:
18
March 2020

The US Food and Drug Administration (FDA) has officially approved a transdermal patch to treat schizophrenia developed by Hisamitsu Pharmaceutical Co following successful

The US Food and Drug Administration (FDA) has officially approved a transdermal patch to treat schizophrenia developed by Hisamitsu Pharmaceutical Co following successful clinical testing.
The patch contains a formulation of asenapine which is used to manage symptoms of schizophrenia and bipolar disorder and is the first of its kind. Schizophrenia now affects around 20 million people worldwide. It’s a debilitating mental disorder that can cause hallucinations, delusions and trouble concentrating.

Richmond Pharmacology are proud to have been involved in the patch’s development since 2014 when we investigated its effectiveness in patients during early-phase testing. Patients reported feeling happier and noted fewer side effects compared to tablets and injections.


For schizophrenia patients who, until recently, only had limited therapeutic options, the patch formulation offers several advantages. It delivers asenapine more gradually into the blood stream over a 24-hour period. Gradual absorption has been shown to reduce the side effects of medications. That’s because a smaller amount of a therapeutic compound is delivered over a longer period of time. At the same time, patients experience fewer gastrointestinal complaints because the gut is bypassed.

The patch formulation is also a more comfortable treatment option compared to injections or tablets because patients don’t need to remember to swallow their pills at certain times or have to travel long distances to receive an injection.

The patch passed phase III testing back in 2018 and is now officially available under the brand name Secuado.

Latest news

Upcoming Event

EUFEMED, 3rd Annual Conference, 28-30 April 2021

28-30 April 2021
Dr Jorg Taubel will co-chair a session on day one, which explores how technology has reduced the risks of pandemic effects on Phase I and II trial performance.
View event

What 20 years of clinical research has taught us about our industry and the future of drug development

June 9, 2021
As Richmond Pharmacology approaches its 20th anniversary our co-founder and CEO reflects on the developments, regulatory changes, and innovations within the life science industry in an article in the PharmaTimes.
Read more

Do we still need challenge trials with COVID-19?

April 21, 2021
Nir Eyal and colleagues suggested that the initiation of COVID-19 challenge trials in response to the UK governments’ call in 2020 remained relevant and important despite the development of approved vaccines and the introduction of an aggressive, UK-wide vaccination policy.
Read more

Novel rate-controlled fentanyl patch shows promise in phase I clinical trial

April 1, 2021
Our expertise in ethnic differences and access to over 12,000 first generation Japanese volunteers accelerated our ability to provide robust clinical trial data to support future applications of new chronic pain medicines to the Japanese drug market.
Read more