Authors: Pierpaolo Pellicori MD, John G.F. Cleland MD, PhD, Maria Borentain MD, Jorg Taubel MD, Fraser Graham MB ChB, Javed Khan MB ChB, Dario Bruzzese PhD, Paul Kessler MD, John J.V. McMurray MD, Adriaan A. Voors MD, PhD, Christopher M. O'Connor MD, John R. Teerlink MD, G. Michael Felker MD, MHSIn a recent publication in the European Journal of Heart Failure (November 2023), the impact of cimlanod, a vasodilator, on diuretic response in congestive heart failure patients is explored. Download

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Impact of vasodilators on diuretic response in patients with congestive heart failure: a mechanistic trial of cimlanod (BMS-986231)

For patients with heart failure and congestion, vasodilation with agents such as cimlanod reduces the response to diuretic agents, which may offset any benefit from acute reductions in cardiac preload and afterload.

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